
Charting a new era of antibiotics
Partnered with the Collins Lab at MIT in building the first-ever generative AI platform for novel antibiotic discovery.







Imagine a world in which common diseases become untreatable. That world may soon be a reality.
By 2050, the death toll of AMR is expected to reach 10 million annually, surpassing cancer as a leading cause of death. There is a critical need for new antibiotics — and yet pharmaceutical and biotechnology companies have largely abandoned the space for more lucrative markets.
A Unique Business Model
Insufficient market incentives and rapid antibiotic resistance leave us vulnerable to the most deadly bacteria. Yet in the midst of this antibiotic crisis, another door is opening. Phare Bio launched in 2020 with an ambitious social venture model and the latest advances in machine learning to address this critical need. Phare is building AIBiotics, the world’s first generative AI antibiotics discovery engine, to design and develop novel antibiotics against urgent threats like Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Phare addresses the “valley of death” -- the stage in preclinical development when most drugs fail -- with donor funding, and takes on more costly clinical development with strategic commercial partnerships and company spin-outs. This model enables Phare to develop a novel pipeline of AI-optimized antibiotic candidates, derisk these candidates through preclinical development, and build a sustainable clinical path to ensure that these therapies reach the patients in greatest need.
AIBiotics Generative AI Discovery Platform
Hit-to-Lead
Optimization
Preclinical Development
Clinical Development
Phare streamlines and optimizes the development process by integrating world-class expertise and decades of experience in artificial intelligence (AI), bioengineering, and pharmaceutical development to rapidly discover and develop novel classes of antibiotics. This unique and self-sustaining approach will enable us to outpace the emergence and global dissemination of antibiotic resistance.